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Their mealtime insulin was stopped on the day of their first dose of semaglutide, which was titrated gradually from 0.25 mg weekly to 1 mg over the following 12 weeks

However, without appropriate nutritional guidance and support from healthcare professionals, there is a real risk that reduced food intake could compromise dietary quality, meaning people may not get enough protein, fibre, vitamins, and minerals essential for maintaining overall health. Guidelines from the National Institute for Health and Care Excellence (NICE) recommend semaglutide as an option for weight management for individuals who meet specific criteria, such as a body mass index (BMI) of at least 35.0 kg/m2 and comorbidity (that is, they also have other conditions such as type 2 diabetes, cardiovascular disease, etc)