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The saturation heuristic is best understood as a plausibility argument for why a figure near 100 mcg is not obviously absurd, not as evidence that it is correct
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Bonafe M, Olivieri F: Genetic polymorphism in long-lived people: cues for the presence of an insulin/IGF-pathway-dependent network affecting human longevity
Reduced glucose, insulin and IGF-1 levels ormore generallyDR activate an energy-sensing network consisting of AMPK, SIRT1, PPAR and PGC-1 with the potential to counteract tumor cell proliferation
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