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Paudel YN, et al

At the same time, it suppresses the production of pheomelanin, a lighter pigment with lower chemical stability, which, when exposed to UV radiation, increases free radical formation and the risk of cellular mutations

These mechanisms are similar in that both induce the transition in the conformation of GLP-1 receptor through van der Waals interactions and hydrogen bonding of Trp33 ECD with extracellular loop (ECL) 1 and ECL2, instead of direct interaction of the peptide with ECL2 [43]

A separate study in Clinical Nutrition (2016) tested glycine supplementation during calorie restriction in obese mice