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Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7), a Phase 3b trial of semaglutide, demonstrated that semaglutide was superior to dulaglutide in improving glycemic control and weight loss 10

Side effects can often be minimized by following the recommended dosage escalation schedule, staying well hydrated, eating smaller meals, and avoiding high-fat foods during dose increases

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