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Antioxidant therapy for cancer faces challenges such as the dual role of ROS in cancer, redox adaptation in cancer cells, interference with pro-oxidant therapies, and heterogeneous response to antioxidants

In a mouse model of hepatocellular carcinoma induced by diethylnitrosamine (DEN), liver GCN5L1 knockout increased DEN sensitivity in the model

This is why the delivery method is just as important as the ingredient itself

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