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A reputable doctor will do three things before prescribing any medication, including GLP-1 prescriptions: Ask questions about your medical history Make sure the patient meets the requirements for the prescription Take time to discuss the indications, contraindications, and known side effects and risks of medication before prescribing it Additionally, if a physician prescribes a medication off-label for weight loss to a patient who qualifies, they can discuss whether the benefits outweigh the risks

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Higher baseline HOMA-IR may favor tirzepatide's dual mechanism

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