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Table 1 summarizes the effect of LTF on the intensity of induced OJ

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Furthermore, the impairment of some androgenic key enzymes and those related to the activity of seminiferous epithelium, together with the decrease in testosterone levels, could suggest an impairment of gonadal function through the alteration of some cellular pathways typically associated with tobacco consumption (Figure 8)

Impurities and degradation products alter receptor binding profiles, increasing off-target effects and reducing melanogenic efficacy