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Hexarelin produces direct, GH-independent cardioprotection via CD36

In experimental systems, DSIP has been shown to influence second messenger activity and hormonal signaling cascades linked to the hypothalamicpituitaryadrenal axis, including regulation of adrenocorticotropic hormone and related endocrine mediators [4]

In addition, systemic intravenous injection of this compound was found to yield severe tachycardia and arrhythmias in non-diabetic and diabetes cases in the swine model