[131] [132] Species from the following genera and the following individual species are known to synthesize B 12 : Propionibacterium shermanii , Pseudomonas denitrificans , Streptomyces griseus , Acetobacterium , Aerobacter , Agrobacterium , Alcaligenes , Azotobacter , Bacillus , Clostridium , Corynebacterium , Flavobacterium , Lactobacillus , Micromonospora , Mycobacterium , Nocardia , Proteus , Rhizobium , Salmonella , Serratia , Streptococcus and Xanthomonas
The key differences are: They often appear suddenly Usually dont have blackheads or closed comedones Can have papules, pustules, and sometimes nodules or cysts, Often caused by external triggers, such as the introduction of medications (like B12 injections or steroids)
The 2024 metabolic study also investigated plasma exposure and tissue distribution in mice after different experimental routes
Indications Symptomatic and short term treatment when the patient does not respond to the monotherapy of acute inflammatory processes with neurotic, musculoskeletal contractures-sciatica