This may result in sense loss, difficulty in proprioception, neuropathic pain, difficulty walking, poor balance, loss of sensation in the feet, muscle weakness, blurred vision (either due to retinopathy [27] or optic neuropathy [28] ), impaired urination, fertility problems, decreased sense of taste and smell, decreased level of consciousness, changes in reflexes, memory loss, mood swings, depression, irritability, cognitive impairment, confusion, anxiety, clumsiness, dementia, and, in more severe cases, psychosis
[8] The age-related decline and its implications The decline of circulating GHK from 200 ng/mL at age 20 to 80 ng/mL by age 60 correlates with reduced wound healing capacity, thinner skin, decreased collagen density, and slower tissue repair
DOI: 10.1210/jc.2015-3754
K.et al (2025)