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semaglutide for obesity showed tirzepatide 10 mg or 15 mg produced significantly greater reductions in body weight and waist circumference over 72 weeks compared to semaglutide 1.7 mg or 2.4 mg, with both drugs having mostly mild-to-moderate gastrointestinal side effects during dose escalation

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In animal studies, this medication has been found to raise the risk of thyroid C-cell tumors, but it is not known if this applies to humans