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Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for the treatment of type 2 diabetes mellitus and, more recently, for weight management in adults with obesity or overweight with weight-related comorbidities, as per the MHRA-approved Summary of Product Characteristics (SmPC) for Mounjaro

Notably, 100% of participants in both the 8 mg and 12 mg groups achieved at least 5% body weight reduction, with 83% of the 12 mg group achieving reductions of 15% or more

Some common medication interactions to be careful of include: Utilizing Rybelsus in conjunction with insulin or insulin secretagogues (such as sulfonylureas) may elevate the likelihood of hypoglycemia, or low blood sugar

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