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Alternatives to Weight Loss Medications If you are looking to lose weight but weight loss medications arent an option due to cost, side effects, health conditions or other factors, there are alternatives outside of diet and exercise to consider: Weight loss surgery like gastric sleeve, Lap-Band and gastric bypass Weight loss programs like Nutrisystem , Noom and WW Liposuction Non-invasive fat removal treatments like fat freezing, radiofrequency treatments and laser fat removal The Bottom Line While not a one-size-fits-all solution, weight loss medications can be a powerful tool for those dealing with obesity