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Liver cells, or hepatocytes, are especially vulnerable to oxidative stress, inflammatory responses, hypoxic conditions, and endoplasmic reticulum stress

One plausible explanation is that triglyceride synthesis serves to secure energy deposits, thus mitigating the risk of passive dependence on environmental nutrients, as discussed earlier

Sin embargo, tambin es capaz de participar en la conjugacin no enzimtica de algunos productos qumicos, como en el caso de la N-acetil-p-benzoquinona imina (NAPQI), el metabolito reactivo formado por la accin del sistema citocromo P450 sobre el paracetamol (o acetaminofeno, como se conoce en los Estados Unidos)

Methods: Vitamin B 12 test results were retrospectively collected from administrative datasets of Brazils public and private healthcare systems between 2016 and 2023