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"GLP-1 agonists like Ozempic work by mimicking a natural gut hormone, but because GLP-1 receptors exist throughout your body, like in your stomach, brain, pancreas, and gallbladder, the effects extend beyond just basic appetite suppression," he said

Consistent with this, adenoviral overexpression of PCSK1 in -cells increases islet GLP-1 production and secretion, ultimately leading to enhanced glucose-stimulation of insulin secretion and improved survival of the islets [165]

The HGF/c-Met pathway is one of the brain's core growth and repair systems

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