why not use dpp4 and glp 1 together Mechanism of action for GIP, GLP-1 analogues inhibitors in DPP-4 Enzyme: The GLP-1 Breakdown

[Same as reference 23] See, K

If there is a discrepancy in columella height between the two sides, we will consider a rotation-advancement repair on the complete side to increase columellar length and a straight-line closure on the incomplete side

Side Effects & Safety No lethal dose found -- toxicology studies couldn't establish an LD50 (Sikiric et al., 2006) No organ toxicity in chronic dosing No hormonal effects -- doesn't affect testosterone, estrogen, cortisol, or GH Mild nausea -- mostly with oral dosing Brief lightheadedness -- occasionally after injection Injection site redness -- standard for SC peptides Angiogenesis concern -- promotes new blood vessel growth, which raises a theoretical question about existing tumors

From a pharmacovigilance perspective, phentermine shows fewer serious adverse events than several newer agents when prescribed as monotherapy