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In contrast, Zepbound, a form of tirzepatide, operates as a dual agonist for both the glucose-dependent insulinotropic polypeptide (GIP) and the GLP-1 receptor, promoting insulin secretion and sensations of satiety

Tirzepatide represents a dual agonist, targeting both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, which may explain its enhanced efficacy in clinical trials

Understanding individual variation Research into genetic variation affecting MOTS-c response could allow more personalized approaches

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