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This process is called the astrocyte-neuron lactate shuttle (Zhang et al

The reaction was developed by using 20 mg 3-3-diaminobenzidine tetrahydrochloride (DAB, Wako pure chemical industries, Ltd) in 40 ml PBST, pH 7.2 containing 10 ml of hydrogen peroxide (H 2 O 2 ) for 7-9 min at a dark room followed by distilled water then dehydrated and mounted

Several viral infections, and the progression of virus-induced diseases, especially those associated with COVID-19, are characterized by an alteration in the intracellular redox balance (Polonikov, 2020)

Ethics statement The studies involving humans were approved by the Quadram Institute Bioscience Human Research Governance Committee (QIB01/2024) and the South East Scotland Research Ethics Committee (24/SS/0047)