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The SDS-PAGE migration of -IGF-1R from GNE knockdown cell extracts was altered, and was similar to neuraminidase (C

10 l of the resulting supernatant was collected for Western blot and the remaining was carefully aspirated

[PubMed: 11158061] 340

Due to the variability in response and other factors, finding new, more effective interventions is always a worthwhile effort. Jennifer Cheng, DO, chief of endocrinology at Hackensack Meridian Jersey Shore University Medical Center in New Jersey, agreed that obesity and weight loss are multifactorial, and there is still research needed to help determine who will be successful in weight loss and who will not respond