doi: 10.3389/fphar.2024.1461995 Received 09 July 2024 Accepted 03 October 2024 Published 17 October 2024 Volume 15 - 2024 Edited by Agnieszka Zelek-Molik, Polish Academy of Sciences, Poland Reviewed by Gilmara Gomes de Assis, So Paulo State University, Brazil Justyna Kusmierczyk, University School of Physical Education in Krakow, Poland Updates Copyright 2024 Liu, Fu, Zhao, Cui and Yang
Number needed to treat (NNT) measures were applied to estimate the treatment effectiveness for clinical outcomes in this CEA
Cortistatin promotes this synchronization directly Homeostatic regulation -- preprocortistatin mRNA is upregulated after sleep deprivation and follows a circadian rhythm, indicating that cortistatin functions as an endogenous homeostatic sleep factor BDNF-dependent expression -- brain-derived neurotrophic factor regulates cortistatin expression in an activity-dependent manner, linking neuronal activity during wakefulness to subsequent sleep drive Cortistatin's receptor pharmacology is well-defined
doi: 10.3390/molecules24132362 79 MahatoD
