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Some of those include metformin which is used in type 2 diabetes, heartburn medications that alter the production of stomach acid such as PPIs or H2 blockers, and oral contraceptives

Over time, these combined effects of stress and environmental factors can result in a compromised skin barrier, decreased collagen production, and an overall loss of elasticity, contributing to a less vibrant and youthful appearance

12 This same effect was not observed with the administration of oral formulation of ALA, where the use of 1200 mg/d for 2 years was not found to have a significant difference in adverse reactions compared to placebo

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