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The epidemiology of coexisting iodine and selenium deficiencies in central Africa, but not in China, has been linked to myxedematous cretinism, a severe form of congenital hypothyroidism accompanied by mental and physical retardation

In the UK, NICE guidance (NG28) recommends considering GLP-1 receptor agonists for patients with type 2 diabetes according to specific criteria, typically when treatment with metformin and other oral medications has not achieved adequate glycaemic control