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Vascular smooth muscle cells were passaged every 3 or 4 d, and all experiments were performed between passages 3 and 6 from the primary culture

The second study compared people on tirzepatide after they underwent a procedure to replace their hearts aortic valve

Expanded obesity drug coverage can increase Medicaid spending and put pressure on overall state budgets, and states are now facing tighter budget conditions and longer-term fiscal uncertainty, due in part to the federal Medicaid cuts in the 2025 reconciliation law, causing state Medicaid programs to re-evaluate their obesity drug coverage

Community observations should inform but not replace careful individual risk assessment