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Description

Its been noted that folic acid fortification in food helps to lower the prevalence of neural tube defects by about 50% to 70%

Depends on the research question

This reversal was seen also on the background of the disturbed prostaglandins- and NO-systems, prostaglandins synthesis inhibition as well as NO-overstimulation (NOS-substrate L-arginine) or NO-blockade (N(G)-nitro-L-arginine methyl ester (L-NAME)) (Stupnisek et al., 2012