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These changes create NDP--MSH (Nle4, D-Phe7--MSH), which is approximately 100-1000 times more potent than native -MSH at the MC1R receptor and is resistant to enzymatic degradation

Histamines are compounds released by cells in response to injury or allergic reactions

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When to Seek Medical Advice About Digestive Side Effects Seek urgent medical attention if sulphur burps are accompanied by severe abdominal pain radiating to the back, persistent vomiting, bloody stools, or jaundice, as these may indicate serious conditions such as pancreatitis or gallbladder disease