thioredoxin glutathione reductase Crystal structure of the human reductase–thioredoxin complex Regulation of the redox homeostasis

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The heterogeneous nature of this ensemble could have contributed to the poor recognition of the severity of the disease

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Decreased levels of GSH, GPx, cysteine, and methionine, and increases in GSSG concentrations, compared with controls, have been shown in a number of studies, whereas levels of homocysteine, SOD, and cystathionine have not been shown to be consistently different between children with autism and controls [163]