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Activation of Nrf2 in defense against cadmium-induced oxidative stress

King WC, Hinerman AS, Courcoulas AP

Loss of GPX4 protein expression in NRF1-deficient cells sensitized cells to ferroptosis, whereas in cells lacking GPX4, overexpression of NRF1 failed to inhibit ferroptosis

The result confirmed the biological effects of hydrogen and put forward a new and promising method for the treatment of this common chronic airway disease