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Dadas las diferencias en dieta, metabolismo y hbitos de salud entre poblaciones, los autores subrayan la necesidad de evaluar estos tratamientos en contextos ms diversos

Best taken on empty stomach at least 10 minutes before meals

Patients should inform their healthcare providers about any kidney disease, significant weight changes, or other medications they are taking, as these factors may influence both the therapeutic effects and elimination timeline of GLP-1 receptor agonists

417,418 The every-other-day fasting (EODF) regimen selectively stimulates beige fat development within white adipose tissue and shifts the gut microbiota composition in experimental models, explaining the mechanism through which IF ameliorates obesity, insulin resistance, and hepatic steatosis