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Lycopene has numerous pharmacological properties including potent and effective anti-inflammatory, immunostimulant, antibacterial, and anti-mutagenic properties (Mller et al

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(Although multiple sclerosis (MS) is classically an autoimmune inflammatory demyelinating disease rather than a primary proteinopathy, we include it here due to overlapping chronic CNS injury and immune dysregulation influenced by the microbiome.) For each disease, specific microbial taxa, metabolites, and pathways implicated in pathogenesis are discussed