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However, much less attention has been paid by medicinal chemists to the field of developing brain targeting drug delivery systems or organ targeting drug delivery systems in a more general perspective via modification of an existing drug delivery system

mitochondrial redox homeostasis 157,158

In particular, the activity of -GCS showed a strong correlation ( r = 0.8939) with GSH production, suggesting that oxidative stress might promote the expression of GSH-related synthetic genes

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