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Importantly, the IGF-1R is also critical for the increased expression of StAR under FSH stimulation, which is required for mitochondrial transport of cholesterol for the first step of sex steroid synthesis, pregnenolone production (60)

Animals Twenty-four, 6-week-old male albino rats weighing between 220 and 250 g were used in this study

Symptoms include dizziness, weakness, confusion, and irritability

We hypothesize that the limited neuroprotection of GTN observed in these studies was attributable to its administration without concurrent revascularization, and that transdermal GTN patches may not have reached the optimal therapeutic levels required for neuroprotection in AIS