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Mortality was 36.8% in the SJS subgroup and higher in the TEN subgroup at 44.4% (4/9), consistent with the higher lethality of TEN reported in previous studies ( The median latency to onset was 9 days (interquartile range [IQR] 314.5 days) for the overall cohort, 14 days (IQR 321) for SJS, and 10 days (IQR 420) for TEN

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Giles FJ, Miller CB, Hurd DD, Wingard JR, Fleming TR, Sonis ST, Bradford WZ, Pulliam JG, Anaissie EJ, Beveridge RA, Brunvand MM, Martin PJ, PROMPT-CT Trial Investigators: A phase III, randomized, double-blind, placebo-controlled, multinational trial of iseganan for the prevention of oral mucositis in patients receiving stomatotoxic chemotherapy (PROMPT-CT trial)

Tricyclic Imidazopyridine Analogs A viable asymmetric synthesis of a new aminopiperidine-fused imidazopyridine DPP-4 inhibitor has been established (116)