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Immunogenetics of autoimmune thyroid diseases: a comprehensive review

Certain medical conditions and medications increase B12 requirements: Long-term use of metformin (diabetes medication) or proton pump inhibitors (PPIs for acid reflux) can impair B12 absorption [13] [14] Gastrointestinal conditions such as Crohn's disease, coeliac disease, or previous gastric surgery Autoimmune conditions beyond pernicious anaemia may affect B12 metabolism When to contact your GP : If you are taking B12 supplements or receiving injections but continue to experience symptoms, request a review

The exceptions are the ones that went through the full pharmaceutical pipeline: insulin, GLP-1 drugs like semaglutide, and a handful of others

Heart rate variability in type 2 diabetes mellitus: a systematic review and metaanalysis