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Stop GLP-1 RAs or tirzepatide if BMI drops below 18.5 kg/m

Unlike earlier medications in this therapeutic space, retatrutide simultaneously activates three hormone receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor

To verify this hypothesis, we designed a randomized controlled study to determine the effect of 4 g/day of intravenous L-carnitine administration on fatigue, hunger, body mass, lipid profile, and other CHD risk factors in MetS patients during a modified fasting period