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Experimental autoimmune thyroiditis (EAT) models have demonstrated that pharmacological blockade of S1P signaling ameliorates thyroid inflammation and reduces TSH levels, underscoring a bidirectional crosstalk between thyroid dysfunction and liver inflammation via ECM pathways (93)

Measure the serum acetaminophen concentration, serum transaminases, and PT/INR every 12 to 24 hours in addition to other clinical variables (eg, factor V, presence of encephalopathy)

The potential of LBPs to treat various conditions, including gastrointestinal, metabolic, and immune system disorders is being investigated

Diab Care 36 , 13961405 (2013)