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Our data provoke the hypothesis that RAMP-UP narrows the synaptic plasticity space by adjusting the efficacy of memory formation to increasing lifetime, with the functional and structural AZ status operating a major adjustment screw

Weight changes that happen more steadily from daily habits can jumpstart a level of energy that inspires diet and exercise improvements and may help maintain the achieved weight loss over time

The second mechanism involves inhibition of clonogenic cell growth, potentially via downregulation of RRM2 and DNA damage, leading to accumulation of DNA breaks and cell cycle blockade

The ORAC assay has also been adapted for electrochemical applications