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Martinovits G, Melamed E, Cohen O, Rosenthal J, Uzzan A (1986) Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)
This class of work reports that amylin-mimetic peptides adopt characteristic binding poses while inducing receptor-specific conformational dynamics, providing a molecular framework for interpreting the pharmacological differences between newer acylated analogs such as cagrilintide and older peptides in the family
For most patients, the decision tree is short