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Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder

Carnitine, an essential molecule in cellular lipid transport, may ameliorate metabolic disturbances through various pathways, including regulating fatty acid metabolism, mitigating oxidative stress, and improving mitochondrial function

further notes that NICE CKS guidance states that treatment of B12 deficiency in people with neurologic involvement should include injections on alternate days until there is no further improvement