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Large-scale clinical trials have demonstrated that GLP-1RAs reduce the incidence of major adverse cardiovascular events (MACE), including myocardial infarction (MI) and stroke, through metabolic, anti-inflammatory, and direct cardiac mechanisms in both diabetic and non-diabetic populations [316,317,318]

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In March of this year, Wegovy was approved for overweight or obese patients with cardiovascular disease

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Molecular Aspects of Medicine, 54 , 2836

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