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193 In addition, psychological factors may play a role in some unexplained back pain, which makes it difficult to assess and identify appropriate patients for treatment

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They are characterized by extreme spatiotemporal heterogeneity, as instead of possessing a single unique structure, they exist as dynamic, interconverting ensembles of multiple conformations

Mutations blocking side chain assembly, polymerization, or transport of a Wzy-dependent Streptococcus pneumoniae capsule are lethal in the absence of suppressor mutations and can affect polymer transfer to the cell wall