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This clearly indicated that the expression of hHPN WT could notably reduce the early symptoms of APAP-induced hepatotoxicity in hepsin / mice, i.e., it effectively diminished the severity of these symptoms to levels comparable to those observed in wild-type mice

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Future studies should prioritize translational research efforts that bridge preclinical discoveries with clinical application, as well as investigate APAP-induced hepatotoxicity across diverse demographic and physiological subgroups

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