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As we have documented the tolerability of L-PAM+BSO when supported by autologous stem cell infusion in heavily pretreated relapsed and/or refractory neuroblastoma patients (NANT phase I study, NCT00005835, www.clinicaltrials.gov), using myeloablative L-PAM+BSO is clinically feasible

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However, they need to make sure the supplement provides acceptable amounts of vitamin B12 made from high-quality ingredients

Support the immune system and adrenaline synthesis, offering liver support