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But sizing the full, eventual impact of these drugs remains difficult, given a large number of unknowns/lingering unanswered questions, and the fast pace of change when it comes to continued clinical innovation, as well as the shifting reimbursement and coverage landscape

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After 68 weeks, half of the participants using GLP-1 agonists lost 15% of their body weight, and nearly a third lost 20% (Wilding et al., 2021)