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The improved antioxidant enzymes activity and GSH content of tissues have been also reported after riboflavin administration in rat models of migraine (GSH, microsomal GPx) (Reference Btn, Nazrolu and Demirci24) , hepatotoxicity (CAT, SOD and GSH) (Reference Al-Harbi, Imam and Nadeem25,Reference Bashandy, Ebaid and Moussa26) , ulcerative colitis (SOD and GSH) (Reference Karakoyun, Erta and Yksel27) , anticancer drug-induced toxicity (CAT, SOD and GSH) (Reference Naseem, Hassan and Alhazza28,Reference Salman and Naseem29) , spinal cord injury (SOD and GSH) (Reference Sakarcan, Erahin and Eminolu30) , diabetes (GR, SOD, CAT and GSH) (Reference Alam, Iqbal and Naseem31) and abdominal aortic aneurysm (SOD) (Reference Yu, Morimoto and Yu32)
DSIP remains a research compound in Canada and is not approved for therapeutic use, but its favorable safety profile and unique mechanism have made it increasingly popular among biohackers, athletes, and those struggling with sleep disturbances
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