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Glial innate immunity in neurodegenerative diseases Early studies established that cytosolic DNA can elicit innate immune responses and innate inflammation, inducing type I interferons (IFNs), yet the molecular mechanism underlying this sensing remained unresolved (Seth et al., 2006)

Low-density CD56 (CD56 dim ) subsets occupy more than 90% of peripheral blood NK (pNK) cells and express high levels of perforin, CD16 and killer Ig-like receptors

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Verify that the elevated B 12 test result is not in error due to test interference (e.g., macroB 12 or heterophile antibody interference) by ordering another test (e.g., total homocysteine)