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According to the International Diabetes Federation (IDF) in 2021, approximately 537 million adults aged 2079 worldwide have diabetes, which is expected to rise to 783 million by 2045 ( Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are two important incretin hormones secreted by the intestine that play a key role in maintaining glucose homeostasis ( 2 Methods 2.1 Literature search Retrieval should be conducted using PubMed, EMBASE, and Sino Med databases