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Some research models note mild observations including gastrointestinal effects in certain experimental protocols

Interestingly, while BPC-157 promotes healing-associated angiogenesis, research also demonstrates it can inhibit tumor-promoting effects of VEGF signaling via the MAPK pathway in melanoma cell lines, suggesting context-dependent modulation of vascular growth that may preferentially support physiological tissue repair over pathological neovascularization

These studies support some skin lightening effects of topical, as well as oral glutathione