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Pancreatic cancer has received particular attention due to the pancreatic expression of GLP-1 receptors and early concerns about pancreatitis potentially increasing cancer risk

However, as longer-term research has accumulated, studies now show that while these medications are effective during treatment, many individuals regain weight after discontinuing them, often at a steady rate that can lead back toward pre-treatment weight within approximately one to two years

Proper pharmacy licensure and medical supervision are important but do not replace FDA premarket approval

They may contribute, but current evidence does not confirm a direct causal relationship