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Those treated with an SGLT2i were more than twice as likely to develop a UTI or pyelonephritis than those treated with a GLP-1 RA (RR 2.27 [95% CI 1.12, 4.55] p =0.019)

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This guide walks through the latest clinical evidence, including the 2025 SURMOUNT-5 head-to-head trial, so you can have an informed conversation with your provider

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