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Nutritional Genomics Research (2024) Published in Nutrients , this comprehensive systematic review identified genetic polymorphisms in complement factor H (CFH), APOE, and oxidative stress pathways that modulate individual responses to nutritional interventions, suggesting future personalized approaches to ocular nutrition

One hypothesis for these observed differences is that biological sex influences gut microbial composition through hormone-regulated immune and metabolic pathways, with sex steroid hormones and sex-linked genetic factors shaping the immune environment and selectively supporting the growth of certain microbial taxa (Jaggar et al., 2020)

Epidemiological studies of cataract prevalence indicate that riboflavin intakes of 1.6 to 2.2 mg/day may reduce the risk of developing age-related cataracts

see Panel A of Figure 2